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Enrichment Benefits of Risk Algorithms for Pulmonary Arterial Hypertension Clinical Trials

Rationale: Event-driven primary endpoints are increasingly used in pulmonary arterial hypertension clinical trials, substantially increasing required sample sizes and trial lengths. The U.S. Food and Drug Administration advocates the use of prognostic enrichment of clinical trials by preselecting a...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Scott, Jacqueline V., Garnett, Christine E., Kanwar, Manreet K., Stockbridge, Norman L., Benza, Raymond L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958501/
https://ncbi.nlm.nih.gov/pubmed/32937078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.202002-0357OC
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