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Enrichment Benefits of Risk Algorithms for Pulmonary Arterial Hypertension Clinical Trials
Rationale: Event-driven primary endpoints are increasingly used in pulmonary arterial hypertension clinical trials, substantially increasing required sample sizes and trial lengths. The U.S. Food and Drug Administration advocates the use of prognostic enrichment of clinical trials by preselecting a...
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| Veröffentlicht in: | Am J Respir Crit Care Med |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Thoracic Society
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7958501/ https://ncbi.nlm.nih.gov/pubmed/32937078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.202002-0357OC |
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