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Structural basis for IFN antagonism by human respiratory syncytial virus nonstructural protein 2

Human respiratory syncytial virus (RSV) nonstructural protein 2 (NS2) inhibits host interferon (IFN) responses stimulated by RSV infection by targeting early steps in the IFN-signaling pathway. But the molecular mechanisms related to how NS2 regulates these processes remain incompletely understood....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pei, Jingjing, Wagner, Nicole D., Zou, Angela J., Chatterjee, Srirupa, Borek, Dominika, Cole, Aidan R., Kim, Preston J., Basler, Christopher F., Otwinowski, Zbyszek, Gross, Michael L., Amarasinghe, Gaya K., Leung, Daisy W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958447/
https://ncbi.nlm.nih.gov/pubmed/33649232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020587118
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