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Primary sex determination in birds depends on DMRT1 dosage, but gonadal sex does not determine adult secondary sex characteristics

In birds, males are the homogametic sex (ZZ) and females the heterogametic sex (ZW). Primary sex determination is thought to depend on a sex chromosome gene dosage mechanism, and the most likely sex determinant is the Z chromosome gene Doublesex and Mab-3–Related Transcription factor 1 (DMRT1). To c...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ioannidis, Jason, Taylor, Gunes, Zhao, Debiao, Liu, Long, Idoko-Akoh, Alewo, Gong, Daoqing, Lovell-Badge, Robin, Guioli, Silvana, McGrew, Mike J., Clinton, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958228/
https://ncbi.nlm.nih.gov/pubmed/33658372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020909118
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