Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q

Spontaneous deamination of DNA cytosine and adenine into uracil and hypoxanthine, respectively, causes C to T and A to G transition mutations if left unrepaired. Endonuclease Q (EndoQ) initiates the repair of these premutagenic DNA lesions in prokaryotes by cleaving the phosphodiester backbone 5′ of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Shi, Ke, Moeller, Nicholas H., Banerjee, Surajit, McCann, Jennifer L., Carpenter, Michael A., Yin, Lulu, Moorthy, Ramkumar, Orellana, Kayo, Harki, Daniel A., Harris, Reuben S., Aihara, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958190/
https://ncbi.nlm.nih.gov/pubmed/33658373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021120118
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados