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How Hydrogen Bonding Amplifies Isomeric Differences in Pyridones toward Strong Changes in Acidity and Tautomerism
[Image: see text] Steric hindrance of hydration and hydrogen bond enhancement by localized charges have been identified as key factors for the massive chemical differences between the hydroxypyridine/pyridone isomers in aqueous solution. While all isomers occur mainly in the hydroxypyridine form in...
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| Publicat a: | J Phys Chem B |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical
Society
2021
|
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7957858/ https://ncbi.nlm.nih.gov/pubmed/33562959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.0c10873 |
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