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TRAF4/6 Is Needed for CD44 Cleavage and Migration via RAC1 Activation

SIMPLE SUMMARY: Tumor cells receive signals from the surrounding extracellular matrix that affect their growth and survival. An important component of the extracellular matrix is the large polysaccharide hyaluronan, which binds and activates certain receptors at the cell surface, including CD44. Act...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Kolliopoulos, Constantinos, Chatzopoulos, Athanasios, Skandalis, Spyros S., Heldin, Carl-Henrik, Heldin, Paraskevi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957764/
https://ncbi.nlm.nih.gov/pubmed/33804427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051021
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