Apoptotic Blocks in Primary Non-Hodgkin B Cell Lymphomas Identified by BH3 Profiling

SIMPLE SUMMARY: The BCL2 protein is expressed in many non-Hodgkin lymphomas (NHLs) as well as associated leukemias, e.g., chronic lymphocytic leukemia (CLL). It functions as a cell survival protein that reduces that ability of a cell to undergo mitochondrial apoptosis. However, the BCL2 inhibitor ve...

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Publicat a:Cancers (Basel)
Autors principals: Rys, Ryan N., Wever, Claudia M., Geoffrion, Dominique, Goncalves, Christophe, Ghassemian, Artin, Brailovski, Eugene, Ryan, Jeremy, Stoica, Liliana, Hébert, Josée, Petrogiannis-Haliotis, Tina, Dmitrienko, Svetlana, Frenkiel, Saul, Staiger, Annette, Ott, German, Steidl, Christian, Scott, David W., Sesques, Pierre, del Rincon, Sonia, Mann, Koren K., Letai, Anthony, Johnson, Nathalie A.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957722/
https://ncbi.nlm.nih.gov/pubmed/33670870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051002
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