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Capsid and Genome Modification Strategies to Reduce the Immunogenicity of Adenoviral Vectors
Adenovirus-based gene transfer vectors are the most frequently used vector type in gene therapy clinical trials to date, and they play an important role as genetic vaccine candidates during the ongoing SARS-CoV-2 pandemic. Immediately upon delivery, adenovirus-based vectors exhibit multiple complex...
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| Опубликовано в: : | Int J Mol Sci |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7957472/ https://ncbi.nlm.nih.gov/pubmed/33670859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052417 |
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