Tropism-Modification Strategies for Targeted Gene Delivery Using Adenoviral Vectors

Achieving high efficiency, targeted gene delivery with adenoviral vectors is a long-standing goal in the field of clinical gene therapy. To achieve this, platform vectors must combine efficient retargeting strategies with detargeting modifications to ablate native receptor binding (i.e. CAR/integrin...

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Main Authors: Coughlan, Lynda, Alba, Raul, Parker, Alan L., Bradshaw, Angela C., McNeish, Iain A., Nicklin, Stuart A., Baker, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2010
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Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185574/
https://ncbi.nlm.nih.gov/pubmed/21994621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v2102290
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