P62‐positive aggregates are homogenously distributed in the myocardium and associated with the type of mutation in genetic cardiomyopathy

Genetic cardiomyopathy is caused by mutations in various genes. The accumulation of potentially proteotoxic mutant protein aggregates due to insufficient autophagy is a possible mechanism of disease development. The objective of this study was to investigate the distribution in the myocardium of suc...

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Опубликовано в: :J Cell Mol Med
Главные авторы: van der Klooster, Zoë Joy, Sepehrkhouy, Shahrzad, Dooijes, Dennis, te Rijdt, Wouter P., Schuiringa, Frederique S. A. M., Lingeman, Jolanthe, van Tintelen, Johannes Peter, Harakalova, Magdalena, Goldschmeding, Roel, Suurmeijer, Albert J. H., Asselbergs, Folkert W., Vink, Aryan
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2021
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957157/
https://ncbi.nlm.nih.gov/pubmed/33605084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16388
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