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The Interleukin-33/ST2 Pathway Is Expressed in the Failing Human Heart and Associated with Pro-fibrotic Remodeling of the Myocardium

The interleukin-33 (IL-33)/suppression of tumorigenicity 2 (ST2) pathway is a potential pathophysiological mediator of cardiac fibrosis. Soluble ST2 (sST2) is one of the main isoforms of ST2 with strong prognostic value in cardiac disease. The exact role of sST2 in cardiac fibrosis is unknown. The a...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Transl Res
Main Authors: Tseng, Cheyenne C. S., Huibers, Manon M. H., van Kuik, Joyce, de Weger, Roel A., Vink, Aryan, de Jonge, Nicolaas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846972/
https://ncbi.nlm.nih.gov/pubmed/29285671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-017-9775-8
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