Decreased miR-214–3p activates NF-κB pathway and aggravates osteoarthritis progression

BACKGROUND: Osteoarthritis (OA), a disease with whole-joint damage and dysfunction, is the leading cause of disability worldwide. The progressive loss of hyaline cartilage extracellular matrix (ECM) is considered as its hallmark, but its exact pathogenesis needs to be further clarified. MicroRNA(miR...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Cao, Yumei, Tang, Su'an, Nie, Xiaoyu, Zhou, Zuoqing, Ruan, Guangfeng, Han, Weiyu, Zhu, Zhaohua, Ding, Changhai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957119/
https://ncbi.nlm.nih.gov/pubmed/33714889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103283
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