Decreased miR-214–3p activates NF-κB pathway and aggravates osteoarthritis progression

BACKGROUND: Osteoarthritis (OA), a disease with whole-joint damage and dysfunction, is the leading cause of disability worldwide. The progressive loss of hyaline cartilage extracellular matrix (ECM) is considered as its hallmark, but its exact pathogenesis needs to be further clarified. MicroRNA(miR...

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Publicat a:EBioMedicine
Autors principals: Cao, Yumei, Tang, Su'an, Nie, Xiaoyu, Zhou, Zuoqing, Ruan, Guangfeng, Han, Weiyu, Zhu, Zhaohua, Ding, Changhai
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957119/
https://ncbi.nlm.nih.gov/pubmed/33714889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103283
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