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Decreased miR-214–3p activates NF-κB pathway and aggravates osteoarthritis progression

BACKGROUND: Osteoarthritis (OA), a disease with whole-joint damage and dysfunction, is the leading cause of disability worldwide. The progressive loss of hyaline cartilage extracellular matrix (ECM) is considered as its hallmark, but its exact pathogenesis needs to be further clarified. MicroRNA(miR...

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書誌詳細
出版年:EBioMedicine
主要な著者: Cao, Yumei, Tang, Su'an, Nie, Xiaoyu, Zhou, Zuoqing, Ruan, Guangfeng, Han, Weiyu, Zhu, Zhaohua, Ding, Changhai
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957119/
https://ncbi.nlm.nih.gov/pubmed/33714889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103283
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