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Reversal of the Inflammatory Responses in Fabry Patient iPSC-Derived Cardiovascular Endothelial Cells by CRISPR/Cas9-Corrected Mutation

The late-onset type of Fabry disease (FD) with GLA IVS4 + 919G > A mutation has been shown to lead to cardiovascular dysfunctions. In order to eliminate variations in other aspects of the genetic background, we established the isogenic control of induced pluripotent stem cells (iPSCs) for the ide...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Song, Hui-Yung, Yang, Yi-Ping, Chien, Yueh, Lai, Wei-Yi, Lin, Yi-Ying, Chou, Shih-Jie, Wang, Mong-Lien, Wang, Chien-Ying, Leu, Hsin-Bang, Yu, Wen-Chung, Chien, Chian-Shiu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956852/
https://ncbi.nlm.nih.gov/pubmed/33673551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052381
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