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Synthesis of Novel Pyrido[1,2-c]pyrimidine Derivatives with 6-Fluoro-3-(4-piperidynyl)-1,2-benzisoxazole Moiety as Potential SSRI and 5-HT(1A) Receptor Ligands
Two series of novel 4-aryl-2H-pyrido[1,2-c]pyrimidine (6a–i) and 4-aryl-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine (7a–i) derivatives were synthesized. The chemical structures of the new compounds were confirmed by (1)H and (13)C NMR spectroscopy and ESI-HRMS spectrometry. The affinities of all compo...
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| Publicat a: | Int J Mol Sci |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7956643/ https://ncbi.nlm.nih.gov/pubmed/33652672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052329 |
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