Reversal of Multidrug Resistance by Apolipoprotein A1-Modified Doxorubicin Liposome for Breast Cancer Treatment

Multidrug resistance (MDR) remains a major problem in cancer therapy and is characterized by the overexpression of p-glycoprotein (P-gp) efflux pump, upregulation of anti-apoptotic proteins or downregulation of pro-apoptotic proteins. In this study, an Apolipoprotein A1 (ApoA1)-modified cationic lip...

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I publikationen:Molecules
Huvudupphovsmän: An, Duopeng, Yu, Xiaochen, Jiang, Lijing, Wang, Rui, He, Peng, Chen, Nanye, Guo, Xiaohan, Li, Xiang, Feng, Meiqing
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956628/
https://ncbi.nlm.nih.gov/pubmed/33652957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26051280
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