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Reversal of multidrug resistance in leukemia cells using a transferrin-modified nanomicelle encapsulating both doxorubicin and psoralen

To ameliorate multidrug resistance (MDR) observed in leukemia cells, nanomicelles modified by transferrin (Tf-M-DOX/PSO), coencapsulating doxorubicin (DOX) and psoralen (PSO), were designed, synthesized and tested in K562 and doxorubicin-resistant K562 (K562/DOX) cells. In vitro drug release kinetic...

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Publicat a:Aging (Albany NY)
Autors principals: Wang, He-Wen, Ma, Ke-Ling, Liu, Hua, Zhou, Jia-Yun
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185111/
https://ncbi.nlm.nih.gov/pubmed/32259795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102992
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