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LONP1 Regulates Mitochondrial Accumulations of HMGB1 and Caspase-3 in CA1 and PV Neurons Following Status Epilepticus

Lon protease 1 (LONP1) is a highly conserved serine peptidase that plays an important role in the protein quality control system in mammalian mitochondria. LONP1 catalyzes the degradation of oxidized, dysfunctional, and misfolded matrix proteins inside mitochondria and regulates mitochondrial gene e...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Kim, Ji-Eun, Park, Hana, Kim, Tae-Hyun, Kang, Tae-Cheon
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956547/
https://ncbi.nlm.nih.gov/pubmed/33668863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052275
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