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LONP1 Regulates Mitochondrial Accumulations of HMGB1 and Caspase-3 in CA1 and PV Neurons Following Status Epilepticus

Lon protease 1 (LONP1) is a highly conserved serine peptidase that plays an important role in the protein quality control system in mammalian mitochondria. LONP1 catalyzes the degradation of oxidized, dysfunctional, and misfolded matrix proteins inside mitochondria and regulates mitochondrial gene e...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Ji-Eun, Park, Hana, Kim, Tae-Hyun, Kang, Tae-Cheon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956547/
https://ncbi.nlm.nih.gov/pubmed/33668863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052275
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