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Methylselenol Produced In Vivo from Methylseleninic Acid or Dimethyl Diselenide Induces Toxic Protein Aggregation in Saccharomyces cerevisiae

Methylselenol (MeSeH) has been suggested to be a critical metabolite for anticancer activity of selenium, although the mechanisms underlying its activity remain to be fully established. The aim of this study was to identify metabolic pathways of MeSeH in Saccharomyces cerevisiae to decipher the mech...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Dauplais, Marc, Bierla, Katarzyna, Maizeray, Coralie, Lestini, Roxane, Lobinski, Ryszard, Plateau, Pierre, Szpunar, Joanna, Lazard, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956261/
https://ncbi.nlm.nih.gov/pubmed/33668124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052241
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