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Molecular goniometers for single-particle cryo-electron microscopy of DNA-binding proteins
Correct reconstruction of macromolecular structure by cryo-electron microscopy (cryo-EM) relies on accurate determination of the orientation of single-particle images. For small (<100 kDa) DNA-binding proteins, obtaining particle images with sufficiently asymmetric features to correctly guide ali...
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| Pubblicato in: | Nat Biotechnol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7956247/ https://ncbi.nlm.nih.gov/pubmed/33077960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-0716-8 |
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