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Molecular goniometers for single-particle cryo-electron microscopy of DNA-binding proteins

Correct reconstruction of macromolecular structure by cryo-electron microscopy (cryo-EM) relies on accurate determination of the orientation of single-particle images. For small (<100 kDa) DNA-binding proteins, obtaining particle images with sufficiently asymmetric features to correctly guide ali...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Aksel, Tural, Yu, Zanlin, Cheng, Yifan, Douglas, Shawn M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956247/
https://ncbi.nlm.nih.gov/pubmed/33077960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-0716-8
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