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Foldamer-templated catalysis of macrocycle formation

Macrocycles, compounds containing a ring of 12 or more atoms, find use in human medicine, fragrances and biological ion sensing. The efficient preparation of macrocycles is a fundamental challenge in synthetic organic chemistry because the high entropic cost of large ring closure allows undesired in...

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Bibliographic Details
Published in:Science
Main Authors: Girvin, Zebediah C., Andrews, Mary Katherine, Liu, Xinyu, Gellman, Samuel H.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956107/
https://ncbi.nlm.nih.gov/pubmed/31857487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax7344
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