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Precision genome editing in plants via gene targeting and subsequent break‐induced single‐strand annealing

Genome editing via artificial nucleases such as CRISPR/Cas9 has become popular in plants now. However, small insertions or deletions are major mutations and nucleotide substitutions rarely occur when DNA cleavage is induced. To induce nucleotide substitutions, a base editor utilizing dead or nickase...

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Bibliografske podrobnosti
izdano v:Plant Biotechnol J
Main Authors: Endo, Masaki, Iwakami, Satoshi, Toki, Seiichi
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955887/
https://ncbi.nlm.nih.gov/pubmed/33001567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.13485
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