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Precision Targeted Mutagenesis via Cas9 Paired Nickases in Rice

Recent reports of CRISPR- (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9) mediated heritable mutagenesis in plants highlight the need for accuracy of the mutagenesis directed by this system. Off-target mutations are an important issue when considering f...

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Detalhes bibliográficos
Publicado no:Plant Cell Physiol
Main Authors: Mikami, Masafumi, Toki, Seiichi, Endo, Masaki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867050/
https://ncbi.nlm.nih.gov/pubmed/26936792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/pcp/pcw049
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