Metabotropic glutamate type 5 receptor binding availability during dextroamphetamine sensitization in mice and humans

BACKGROUND: Glutamate transmission is implicated in drug-induced behavioural sensitization and the associated long-lasting increases in mesolimbic output. Metabotropic glutamate type 5 (mGlu5) receptors might be particularly important, but most details are poorly understood. METHODS: We first assess...

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Veröffentlicht in:J Psychiatry Neurosci
Hauptverfasser: Smart, Kelly, Nagano-Saito, Atsuko, Milella, Michele S., Sakae, Diana Yae, Favier, Mathieu, Vigneault, Erika, Louie, Leanne, Hamilton, Alison, Ferguson, Stephen S.G., Rosa-Neto, Pedro, Narayanan, Sridar, Mestikawy, Salah El, Leyton, Marco, Benkelfat, Chawki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Joule Inc. 2021
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955855/
https://ncbi.nlm.nih.gov/pubmed/32559027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.190162
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