Precisely Fabricated Sulpiride-Loaded Nanolipospheres with Ameliorated Oral Bioavailability and Antidepressant Activity

BACKGROUND: Sulpiride (SUL), is a selective antidopaminergic drug that had extensive biological activities. However, its sparingly aqueous solubility and limited gastrointestinal permeability lead to scanty oral bioavailability which hinders its clinical efficacy. OBJECTIVE: SUL-loaded lipospheres (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Nanomedicine
Prif Awduron: Mohyeldin, Salma M, Samy, Wael M, Ragab, Doaa, Abdelmonsif, Doaa A, Aly, Rania G, Elgindy, Nazik A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove 2021
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955741/
https://ncbi.nlm.nih.gov/pubmed/33727812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S296726
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