Impact of Sirolimus as a Primary Immunosuppressant on Myocardial Fibrosis and Diastolic Function Following Heart Transplantation

BACKGROUND: Myocardial fibrosis is an important contributor for development of diastolic dysfunction. We investigated the impact of sirolimus as primary immunosuppression on diastolic dysfunction and fibrosis progression among heart transplantation recipients. METHODS AND RESULTS: In 100 heart trans...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Alnsasra, Hilmi, Asleh, Rabea, Oh, Jae K., Maleszewski, Joseph J., Lerman, Amir, Toya, Takumi, Chandrasekaran, Krishnaswamy, Bois, Melanie C., Kushwaha, Sudhir S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955460/
https://ncbi.nlm.nih.gov/pubmed/33325244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.018186
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