Canagliflozin Suppresses Atrial Remodeling in a Canine Atrial Fibrillation Model

BACKGROUND: Recent clinical trials have demonstrated the possible pleiotropic effects of SGLT2 (sodium–glucose cotransporter 2) inhibitors in clinical cardiovascular diseases. Atrial electrical and structural remodeling is important as an atrial fibrillation (AF) substrate. METHODS AND RESULTS: The...

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Pubblicato in:J Am Heart Assoc
Autori principali: Nishinarita, Ryo, Niwano, Shinichi, Niwano, Hiroe, Nakamura, Hironori, Saito, Daiki, Sato, Tetsuro, Matsuura, Gen, Arakawa, Yuki, Kobayashi, Shuhei, Shirakawa, Yuki, Horiguchi, Ai, Ishizue, Naruya, Igarashi, Tazuru, Yoshizawa, Tomoharu, Oikawa, Jun, Hara, Yoshinobu, Katsumura, Takafumi, Kishihara, Jun, Satoh, Akira, Fukaya, Hidehira, Sakagami, Hiroyuki, Ako, Junya
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955321/
https://ncbi.nlm.nih.gov/pubmed/33399004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.017483
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