Canagliflozin Suppresses Atrial Remodeling in a Canine Atrial Fibrillation Model

BACKGROUND: Recent clinical trials have demonstrated the possible pleiotropic effects of SGLT2 (sodium–glucose cotransporter 2) inhibitors in clinical cardiovascular diseases. Atrial electrical and structural remodeling is important as an atrial fibrillation (AF) substrate. METHODS AND RESULTS: The...

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Détails bibliographiques
Publié dans:J Am Heart Assoc
Auteurs principaux: Nishinarita, Ryo, Niwano, Shinichi, Niwano, Hiroe, Nakamura, Hironori, Saito, Daiki, Sato, Tetsuro, Matsuura, Gen, Arakawa, Yuki, Kobayashi, Shuhei, Shirakawa, Yuki, Horiguchi, Ai, Ishizue, Naruya, Igarashi, Tazuru, Yoshizawa, Tomoharu, Oikawa, Jun, Hara, Yoshinobu, Katsumura, Takafumi, Kishihara, Jun, Satoh, Akira, Fukaya, Hidehira, Sakagami, Hiroyuki, Ako, Junya
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955321/
https://ncbi.nlm.nih.gov/pubmed/33399004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.017483
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