Canagliflozin Suppresses Atrial Remodeling in a Canine Atrial Fibrillation Model

BACKGROUND: Recent clinical trials have demonstrated the possible pleiotropic effects of SGLT2 (sodium–glucose cotransporter 2) inhibitors in clinical cardiovascular diseases. Atrial electrical and structural remodeling is important as an atrial fibrillation (AF) substrate. METHODS AND RESULTS: The...

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Publicado en:J Am Heart Assoc
Autores principales: Nishinarita, Ryo, Niwano, Shinichi, Niwano, Hiroe, Nakamura, Hironori, Saito, Daiki, Sato, Tetsuro, Matsuura, Gen, Arakawa, Yuki, Kobayashi, Shuhei, Shirakawa, Yuki, Horiguchi, Ai, Ishizue, Naruya, Igarashi, Tazuru, Yoshizawa, Tomoharu, Oikawa, Jun, Hara, Yoshinobu, Katsumura, Takafumi, Kishihara, Jun, Satoh, Akira, Fukaya, Hidehira, Sakagami, Hiroyuki, Ako, Junya
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955321/
https://ncbi.nlm.nih.gov/pubmed/33399004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.017483
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