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An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism

The signalling pathways underpinning cell growth and invasion use overlapping components, yet how mutually exclusive cellular responses occur is unclear. Here, we report development of 3-Dimensional culture analyses to separately quantify growth and invasion. We identify that alternate variants of I...

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發表在:Nat Commun
Main Authors: Nacke, Marisa, Sandilands, Emma, Nikolatou, Konstantina, Román-Fernández, Álvaro, Mason, Susan, Patel, Rachana, Lilla, Sergio, Yelland, Tamas, Galbraith, Laura C. A., Freckmann, Eva C., McGarry, Lynn, Morton, Jennifer P., Shanks, Emma, Leung, Hing Y., Markert, Elke, Ismail, Shehab, Zanivan, Sara, Blyth, Karen, Bryant, David M.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955138/
https://ncbi.nlm.nih.gov/pubmed/33712589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21847-4
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