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Joint probabilistic modeling of single-cell multi-omic data with totalVI

The paired measurement of RNA and surface proteins in single cells with CITE-seq is a promising approach to connect transcriptional variation with cell phenotypes and functions. However, combining these paired views into a unified representation of cell state is made challenging by the unique techni...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Gayoso, Adam, Steier, Zoë, Lopez, Romain, Regier, Jeffrey, Nazor, Kristopher L, Streets, Aaron, Yosef, Nir
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954949/
https://ncbi.nlm.nih.gov/pubmed/33589839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-01050-x
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