Lipid-induced endothelial vascular cell adhesion molecule 1 promotes nonalcoholic steatohepatitis pathogenesis

Monocyte homing to the liver and adhesion to the liver sinusoidal endothelial cells (LSECs) are key elements in nonalcoholic steatohepatitis (NASH) pathogenesis. We reported previously that VCAM-1 mediates monocyte adhesion to LSECs. However, the pathogenic role of VCAM-1 in NASH is unclear. Herein,...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Furuta, Kunimaro, Guo, Qianqian, Pavelko, Kevin D., Lee, Jeong-Heon, Robertson, Keith D., Nakao, Yasuhiko, Melek, Jan, Shah, Vijay H., Hirsova, Petra, Ibrahim, Samar H.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954604/
https://ncbi.nlm.nih.gov/pubmed/33476308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI143690
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires