Lipid-induced endothelial vascular cell adhesion molecule 1 promotes nonalcoholic steatohepatitis pathogenesis

Monocyte homing to the liver and adhesion to the liver sinusoidal endothelial cells (LSECs) are key elements in nonalcoholic steatohepatitis (NASH) pathogenesis. We reported previously that VCAM-1 mediates monocyte adhesion to LSECs. However, the pathogenic role of VCAM-1 in NASH is unclear. Herein,...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Furuta, Kunimaro, Guo, Qianqian, Pavelko, Kevin D., Lee, Jeong-Heon, Robertson, Keith D., Nakao, Yasuhiko, Melek, Jan, Shah, Vijay H., Hirsova, Petra, Ibrahim, Samar H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2021
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954604/
https://ncbi.nlm.nih.gov/pubmed/33476308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI143690
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