Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzees

While comparative functional genomic studies have shown that inter-species differences in gene expression can be explained by corresponding inter-species differences in genetic and epigenetic regulatory mechanisms, co-transcriptional mechanisms, such as alternative polyadenylation (APA), have receiv...

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Udgivet i:eLife
Main Authors: Mittleman, Briana E, Pott, Sebastian, Warland, Shane, Barr, Kenneth, Cuevas, Claudia, Gilad, Yoav
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2021
Fag:
Genetics and Genomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954529/
https://ncbi.nlm.nih.gov/pubmed/33595436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62548
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