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Segmental Duplications Contribute to Gene Expression Differences Between Humans and Chimpanzees

In addition to specific changes in cis- and trans-regulatory elements, structural changes in the genome are hypothesized to underlie a large number of differences in gene expression between species. Accordingly, we show that species-specific segmental duplications are enriched with genes that are di...

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Bibliografske podrobnosti
Main Authors: Blekhman, Ran, Oshlack, Alicia, Gilad, Yoav
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691770/
https://ncbi.nlm.nih.gov/pubmed/19332884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.099960
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