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Latrophilin GPCR signaling mediates synapse formation

Neural circuit assembly in the brain requires precise establishment of synaptic connections, but the mechanisms of synapse assembly remain incompletely understood. Latrophilins are postsynaptic adhesion-GPCRs that engage in trans-synaptic complexes with presynaptic teneurins and FLRTs. In mouse CA1-...

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Pubblicato in:eLife
Autori principali: Sando, Richard, Südhof, Thomas C
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954527/
https://ncbi.nlm.nih.gov/pubmed/33646123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65717
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