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Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins
Bidirectional signaling by cell-adhesion molecules is thought to mediate synapse formation, but the mechanisms involved remain elusive. Here we found that the adhesion-G-protein-coupled receptors latrophilin-2 and latrophilin-3 selectively directed formation of perforant-path and Schaffer-collateral...
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| Publicado no: | Science |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6636343/ https://ncbi.nlm.nih.gov/pubmed/30792275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aav7969 |
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