Structural basis for teneurin function in circuit-wiring: A toxin motif at the synapse

Teneurins (TENs) are cell-surface adhesion proteins with critical roles in tissue development and axon guidance. Here we report the 3.1-Å electron cryo-microscopy structure of the human TEN2 extracellular region (ECR), revealing a striking similarity to bacterial Tc-toxins. The ECR includes a large...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell
Autori principali: Li, Jingxian, Shalev-Benami, Moran, Sando, Richard, Jiang, Xian, Kibrom, Amanuel, Wang, Jie, Leon, Katherine, Katanski, Christopher, Nazarko, Olha, Lu, Yue C., Südhof, Thomas C., Skiniotis, Georgios, Araç, Demet
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912346/
https://ncbi.nlm.nih.gov/pubmed/29677516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.03.036
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi