Injury-mediated stiffening persistently activates muscle stem cells through YAP and TAZ mechanotransduction

The skeletal muscle microenvironment transiently remodels and stiffens after exercise and injury, as muscle ages, and in myopathic muscle; however, how these changes in stiffness affect resident muscle stem cells (MuSCs) remains understudied. Following muscle injury, muscle stiffness remained elevat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Adv
Hauptverfasser: Silver, Jason S., Günay, K. Arda, Cutler, Alicia A., Vogler, Thomas O., Brown, Tobin E., Pawlikowski, Bradley T., Bednarski, Olivia J., Bannister, Kendra L., Rogowski, Cameron J., Mckay, Austin G., DelRio, Frank W., Olwin, Bradley B., Anseth, Kristi S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2021
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954458/
https://ncbi.nlm.nih.gov/pubmed/33712460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe4501
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge