Injury-mediated stiffening persistently activates muscle stem cells through YAP and TAZ mechanotransduction

The skeletal muscle microenvironment transiently remodels and stiffens after exercise and injury, as muscle ages, and in myopathic muscle; however, how these changes in stiffness affect resident muscle stem cells (MuSCs) remains understudied. Following muscle injury, muscle stiffness remained elevat...

詳細記述

保存先:
書誌詳細
出版年:Sci Adv
主要な著者: Silver, Jason S., Günay, K. Arda, Cutler, Alicia A., Vogler, Thomas O., Brown, Tobin E., Pawlikowski, Bradley T., Bednarski, Olivia J., Bannister, Kendra L., Rogowski, Cameron J., Mckay, Austin G., DelRio, Frank W., Olwin, Bradley B., Anseth, Kristi S.
フォーマット: Artigo
言語:Inglês
出版事項: American Association for the Advancement of Science 2021
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954458/
https://ncbi.nlm.nih.gov/pubmed/33712460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe4501
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