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Injury-mediated stiffening persistently activates muscle stem cells through YAP and TAZ mechanotransduction
The skeletal muscle microenvironment transiently remodels and stiffens after exercise and injury, as muscle ages, and in myopathic muscle; however, how these changes in stiffness affect resident muscle stem cells (MuSCs) remains understudied. Following muscle injury, muscle stiffness remained elevat...
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| Veröffentlicht in: | Sci Adv |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Association for the Advancement of Science
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7954458/ https://ncbi.nlm.nih.gov/pubmed/33712460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe4501 |
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