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GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells
Glucose-dependent insulinotropic polypeptide (GIP) communicates nutrient intake from the gut to islets, enabling optimal levels of insulin secretion via the GIP receptor (GIPR) on β cells. The GIPR is also expressed in α cells, and GIP stimulates glucagon secretion; however, the role of this action...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7954443/ https://ncbi.nlm.nih.gov/pubmed/33712466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abf1948 |
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