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Transcriptional analysis of islets of Langerhans from organ donors of different ages
Insulin secretion is impaired with increasing age. In this study, we aimed to determine whether aging induces specific transcriptional changes in human islets. Laser capture microdissection was used to extract pancreatic islet tissue from 37 deceased organ donors aged 1–81 years. The transcriptomes...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7954335/ https://ncbi.nlm.nih.gov/pubmed/33711030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247888 |
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