Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors

Cholinergic modulation of hippocampal network function is implicated in multiple behavioral and cognitive states. Activation of nicotinic and muscarinic acetylcholine receptors affects neuronal excitability, synaptic transmission and rhythmic oscillations in the hippocampus. In this work, we studied...

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Bibliographic Details
Published in:PLoS One
Main Authors: Zapukhliak, Olha, Netsyk, Olga, Romanov, Artur, Maximyuk, Oleksandr, Oz, Murat, Holmes, Gregory L., Krishtal, Oleg, Isaev, Dmytro
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954330/
https://ncbi.nlm.nih.gov/pubmed/33711021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240074
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