Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors

Cholinergic modulation of hippocampal network function is implicated in multiple behavioral and cognitive states. Activation of nicotinic and muscarinic acetylcholine receptors affects neuronal excitability, synaptic transmission and rhythmic oscillations in the hippocampus. In this work, we studied...

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Vydáno v:PLoS One
Hlavní autoři: Zapukhliak, Olha, Netsyk, Olga, Romanov, Artur, Maximyuk, Oleksandr, Oz, Murat, Holmes, Gregory L., Krishtal, Oleg, Isaev, Dmytro
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954330/
https://ncbi.nlm.nih.gov/pubmed/33711021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240074
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