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Biological impact of mutually exclusive exon switching

Alternative splicing can expand the diversity of proteomes. Homologous mutually exclusive exons (MXEs) originate from the same ancestral exon and result in polypeptides with similar structural properties but altered sequence. Why would some genes switch homologous exons and what are their biological...

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Publicat a:PLoS Comput Biol
Autors principals: Lam, Su Datt, Babu, M. Madan, Lees, Jonathan, Orengo, Christine A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954323/
https://ncbi.nlm.nih.gov/pubmed/33651795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008708
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