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The potential shared role of inflammation in insulin resistance and schizophrenia: A bidirectional two-sample mendelian randomization study

BACKGROUND: Insulin resistance predisposes to cardiometabolic disorders, which are commonly comorbid with schizophrenia and are key contributors to the significant excess mortality in schizophrenia. Mechanisms for the comorbidity remain unclear, but observational studies have implicated inflammation...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Med
Prif Awduron: Perry, Benjamin I., Burgess, Stephen, Jones, Hannah J., Zammit, Stan, Upthegrove, Rachel, Mason, Amy M., Day, Felix R., Langenberg, Claudia, Wareham, Nicholas J., Jones, Peter B., Khandaker, Golam M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954314/
https://ncbi.nlm.nih.gov/pubmed/33711016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1003455
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