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Investigating causality in associations between smoking initiation and schizophrenia using Mendelian randomization

Smoking is strongly associated with schizophrenia. Although it has been widely assumed that this reflects self-medication, recent studies suggest that smoking may be a risk factor for schizophrenia. We performed two-sample bi-directional Mendelian randomization using summary level genomewide associa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gage, Suzanne H., Jones, Hannah J., Taylor, Amy E., Burgess, Stephen, Zammit, Stanley, Munafò, Marcus R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244403/
https://ncbi.nlm.nih.gov/pubmed/28102331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40653
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