Case Report: Targeting 2 Antigens as a Promising Strategy in Mixed Phenotype Acute Leukemia: Combination of Blinatumomab With Gemtuzumab Ozogamicin in an Infant With a KMT2A-Rearranged Leukemia

Mixed phenotype acute leukemia (MPAL) accounts for 2-5% of leukemia in children. MPAL are at higher risk of induction failure. Lineage switch (B to M or vice versa) or persistence of only the lymphoid or myeloid clone is frequently observed in biphenotypic/bilineal cases, highlighting their lineage...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Brethon, Benoît, Lainey, Elodie, Caye-Eude, Aurélie, Grain, Audrey, Fenneteau, Odile, Yakouben, Karima, Roupret-Serzec, Julie, Le Mouel, Lou, Cavé, Hélène, Baruchel, André
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953899/
https://ncbi.nlm.nih.gov/pubmed/33718232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.637951
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