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Biomarkers of Gemtuzumab Ozogamicin Response for Acute Myeloid Leukemia Treatment
Gemtuzumab ozogamicin (GO, Mylotarg(®)) consists of a humanized CD33-targeted antibody-drug conjugated to a calicheamicin derivative. Growing evidence of GO efficacy in acute myeloid leukemia (AML), demonstrated by improved outcomes in CD33-positive AML patients across phase I to III clinical trials...
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| Veröffentlicht in: | Int J Mol Sci |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7460695/ https://ncbi.nlm.nih.gov/pubmed/32781546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165626 |
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