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Ni-Catalyzed Regioselective 1,2-Dialkylation of Alkenes Enabled by the Formation of Two C(sp(3))−C(sp(3)) Bonds

We disclose a Ni-catalyzed vicinal difunctionalization of alkenes with benzyl halides and alkylzinc reagents, which produces products with two new alkyl–alkyl bonds. This alkene dialkylation is effective in combining secondary benzyl halides and secondary alkylzinc reagents with internal alkenes, wh...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Dhungana, Roshan K., Sapkota, Rishi R., Wickham, Laura M., Niroula, Doleshwar, Giri, Ramesh
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953840/
https://ncbi.nlm.nih.gov/pubmed/33271014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c09778
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